Ask Dr. Sears a Question – Each inquiry is responded to personally by Dr. Sears or a member of his staff.

Dr. Barry Sears is a leading authority on the dietary control of hormonal response. A former research scientist at the Boston University School of Medicine and the Massachusetts Institute of Technology, Dr. Sears has dedicated his research efforts over the past 30 years to the study of lipids. He is the author of more than 50 scientific publications and holds 14 U.S. Patents in the areas of intravenous drug delivery systems and the dietary regulation of hormonal responses for the treatment of cardiovascular disease.

A turning point in his research occurred in 1982. That year the Nobel Prize in Medicine was awarded for discoveries of the role that specialized hormones known as eicosanoids play in the development of cardiovascular disease, diabetes, auto-immune diseases, and cancer. Since eicosanoids are only generated from dietary fat, Dr. Sears reasoned that one could apply intravenous drug-delivery principles to nutrition in order to control these exceptionally powerful hormonal responses with laser-like precision. In essence, his approach treats food as if it were a drug.

This area of his research led to various patents in the area of hormonal control by essentially using food as an oral drug-delivery system to modulate eicosanoids, especially for cardiovascular, diabetic, and neurological patients.

The impact of Dr. Sears’ revolutionary work in the dietary control of hormonal response began with the publication of his landmark book, The Zone. Since its publication in June 1995, The Zone has sold more than 2,000,000 hardcover copies and became a #1 best-seller on the New York Times book list. In addition, The Zone has been translated into 23 languages, indicating a worldwide response to Dr. Sears’ research. His second book, Mastering the Zone, published in 1997, also became a New York Times’ bestseller with hardcover sales in excess of 500,000 copies to date. His third book, Zone Perfect Meals in Minutes, published in 1997, quickly became one of the best-selling cookbooks of 1997 and another New York Times bestseller. The Anti-Aging Zone was published in 1999 and provides the molecular insights into how the Zone Diet can help with the aging process. The OmegaRx Zone, published in 2002, was the first book to explore the role of high-dose fish oil and chronic disease. The Anti-Inflammation Zone, published in 2005, discusses the role of diet-induced inflammation  in the development of cancer, heart disease, diabetes, dementia, and many other inflammatory conditions—and how to reverse these conditions if they are already present. His book Toxic Fat was published in 2008. It goes into detail about how obesity has many similarities to cancer and explains why our current efforts to treat obesity will never be successful if they do not address its underlying cause, which is inflammation. The Mediterranean Zone, released in October 2014, described the role of polyphenols to repair the tissue damage that results from diet-induced inflammation. To date more than 6 million hardcover copies of his books have been sold in the United States. His latest book to be released in September of 2019, The Resolution Zone,  brings together his decades of research to understand the molecular nature of the healing process which is known scientifically as the Resolution Response. Lack of an optimized Resolution Response may represent the underlying cause of all chronic disease.

His research has elevated food from more than simply a source of calories to being recognized as an exceptionally powerful drug. Because of his revolutionary research, Dr. Sears has been a guest on many national programs, such as 20/20, Today, Good Morning America, CBS Morning News, CNN, and MSNBC.

Dr. Sears continues his ongoing research as the president of the non-profit Inflammation Research Foundation in Peabody, MA. In addition to continuing research on the hormonal and genetic effects of food, Dr. Sears has expanded his research in developing innovative dietary approaches used in managing diabetes, cardiovascular disease, and neurological conditions.

View Resume / CV for Dr. Barry Sears.

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Ask Dr. Sears a Question – He responds to all inquiries personally!

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