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Doctor Barry Sears

Dr. Sears Comments:

Unfortunately, the article failed to mention one natural treatment (and I didn't know that electro-convulsive shock therapy is a natural treatment) is high-dose fish oil, especially since it has been proven to be clinically effective.
Doctor Barry Sears

Dr. Sears Comments:

An even simpler test is the AA/EPA ratio from a finger-stick test. Once that ratio decreases significantly, so does the accompanying depression.
Doctor Barry Sears

Dr. Sears Comments:

There is no question that SSRI drugs have their problems in pregnancy. A solution is to use higher doses of fish oil that is excellent for treating depression and ideal for cognitive health of the child.
Doctor Barry Sears

Dr. Sears Comments:

Very striking evidence that serotonin may be the cause of depression.  A more likely candidate is inflammation disrupting the communication of neurotransmitters into the interior of the neuron.  This is why high-dose fish oil is effective in treating depression.
Doctor Barry Sears

Dr. Sears Comments:

It sounds like someone has been reading my books for the past 20 years.
Doctor Barry Sears

Dr. Sears Comments:

Ironically, one the best ways to treat depression and reduce the anxiety that leads to relapse in alcoholism is high-dose fish oil.  It you have either condition, the supplementation with high-dose fish oil will remarkably improve your ability to manage the condition. 
Doctor Barry Sears

Dr. Sears Comments:

Actually, there is a biological linkage between depression and Parkinson's.  It's called neuroinflammation.
Doctor Barry Sears

Dr. Sears Comments:

To maintain weight loss, you have to maintain a calorie-restricted diet.  Such a diet without adequate supplementation with long-chain omega-3 fatty acids can lead to depression.
Doctor Barry Sears

Dr. Sears Comments:

Vitamin D appears to a marker of general good health.  That's why low Vitamin D levels seem to be associated with so many chronic diseases.  However, association is different than causing them.
Doctor Barry Sears

Dr. Sears Comments:

Epigenetics is making the hope of personalized medicine by simply looking at the gene sequences more and more of a pipe dream.  
Doctor Barry Sears

Dr. Sears Comments:

I feel that depression can be transgenerational, mediated by fetal programing.  This means depressed mothers can pass depression characteristics to their children via epigenetics.
Doctor Barry Sears

Dr. Sears Comments:

Electroshock therapy was also initially effective in the treating depression, however, depression has a strong linkage with inflammation. Unless you are following an anti-inflammatory diet supplemented with high-dose fish oil, it is unlikely to have long-lasting effects.
Doctor Barry Sears

Dr. Sears Comments:

Both depression and anxiety are linked to inflammation.  One of the consequences of insomnia is increased insulin levels.  If you mix increased insulin with excess omega-6 fatty acids, then you get more arachidonic acid that leads to inflammation.
Doctor Barry Sears

Dr. Sears Comments:

Both depression and cognitive decline are linked to increased neuroinflammation.  Reduce that inflammation in the brain, and you become happier and smarter.  The best way to do both is through high-dose fish oil. 
Doctor Barry Sears

Dr. Sears Comments:

At least the article hints at inflammation as the linkage of the two conditions.  The fact that high-dose fish oil treats both conditions would also reinforce that inflammatory link.
Doctor Barry Sears

Dr. Sears Comments:

Unfortunately, the treatment for PTSD (i.e. more anti-depressants, etc.) has generated relatively poor results, whereas the indication of much better results using high-dose fish oil remains ignored.
Doctor Barry Sears

Dr. Sears Comments:

Actually depression is like diabetes as both conditions have a strong inflammatory component working in different directions.  In diabetes, the inflammation is disrupting normal glucose metabolism, whereas in depression the inflammation is disturbing the flow of neural transmitters.
Doctor Barry Sears

Dr. Sears Comments:

Stress causes the increased secretion in cortisol that in turn causes insulin resistance.  This is what makes you gain weight.  The increase in blood sugar levels with the saturated-fat meal is probably due to its interaction with TLR-4 receptors in every cell that increases inflammation that leads to insulin resistance.
Doctor Barry Sears

Dr. Sears Comments:

Post-partum depression is simply another form of depression.  It has been shown in clinical trials that high-dose fish oil is very effective in treating depression.  Post-partum depression should be no exception.
Doctor Barry Sears

Dr. Sears Comments:

The clinical data on high-dose fish oil to treat mild to severe depression is much stronger than St. John's wort.  Why not stick with a winner?
Doctor Barry Sears

Dr. Sears Comments:

High-dose fish oil does wonders for both depression and heart disease regardless of gender. 
Doctor Barry Sears

Dr. Sears Comments:

Your best approach to treat depression and prevent weight gain is the use of high-dose fish oil.
Doctor Barry Sears

Dr. Sears Comments:

Screening for depression is difficult especially with the levels dramatically increasing in all sectors of society.
Doctor Barry Sears

Dr. Sears Comments:

Nice try. The FTO variant may account for another 5 pounds of weight.
Doctor Barry Sears

Dr. Sears Comments:

Although both depression and Alzheimer's are characterized by neuroinflammation, it is still not clear about the importance in amyloid plaques as many seniors with them have no indication of Alzheimer's.
Doctor Barry Sears

Dr. Sears Comments:

Bottom line is both anti-depressant use and quitting smoking cause weight gain. Anti-depressants affect the serotonin pathways; lack of smoking affects the dopamine pathways. I believe taking high-dose fish oil can overcome the side-effects of either action because the omega-3 fatty acids will improve both serotonin and dopamine efficacy.
Doctor Barry Sears

Dr. Sears Comments:

High-dose fish oil should be recommended to all depression patients, but apparently it also should be essentially coupled with a strict anti-inflammatory diet for the atypical depressed patient.
Doctor Barry Sears

Dr. Sears Comments:

Omega-3 fatty acids are effective, but you need to take a therapeutic dosage.

Doctor Barry Sears

Dr. Sears Comments:

One of the more consistent successes for treating both uni-polar and bi-polar depression is high-dose fish oil.
Doctor Barry Sears

Dr. Sears Comments:

It's not clear that beta amyloid plaques are the cause of Alzheimer's. They're present in Alzheimer's patients, but they are also present in patients without dementia. The only thing that is truly known to be associated with Alzheimer's is neuroinflammation.
Doctor Barry Sears

Dr. Sears Comments:

With a growing number of articles indicating that anti-depressants have long-term problems (especially if they get into the water supply), finding non-pharmaceutical treatments is paramount. TMS is one of these. High-dose fish oil is another.

Doctor Barry Sears

Dr. Sears Comments:

Before I would go to Botox for treating depression, I would use high-dose fish oil as it has been shown to be very effective in both uni- and bi-polar depression.
Doctor Barry Sears

Dr. Sears Comments:

High-dose fish oil good for treating depression in both males and females. It also makes you happier.

Doctor Barry Sears

Dr. Sears Comments:

The omega-3 fatty acids are fine, it's just the mercury in the tuna and the glucose in the sandwich that are less desirable.
Doctor Barry Sears

Dr. Sears Comments:

It's not surprising that two inflammatory diseases would impact each other.
Doctor Barry Sears

Dr. Sears Comments:

Dendrites expand with brain-derived neurotrophic factor (BDNF) that increases with exercise.
Doctor Barry Sears

Dr. Sears Comments:

Any epidemiology study can only suggest a hypothesis to be tested. So far virtually all intervention trials with Vitamin D have failed. The best you can say about Vitamin D is that may be marker of good health and little less.

Doctor Barry Sears

Dr. Sears Comments:

The best childhood intervention starts at minus nine months with the mother's diet to prevent epigenetic marks that can lead to later chronic disease at an earlier age.
Doctor Barry Sears

Dr. Sears Comments:

Totally overlooked in this article that children with ADHD have low levels of omega-3 fatty acids in the blood and intervention studies with high-dose fish oil indicated statistically significant improvement in the condition.
Doctor Barry Sears

Dr. Sears Comments:

The best way to battle post-partum depression is to maintain adequate levels of omega-3 fatty acids in the blood.